Arylboronic Acids With Strong Fluorescence Intensity Changes Upon Sugar Binding
نویسندگان
چکیده
Boronic acids play an important role in the design and synthesis of chemosensors for carbohydrates due to their ability to reversibly bind with diol-containing compounds. Along this line, the availability of boronic acids that change fluorescence upon sugar binding is critical to a successful sensor design effort. Here, two boronic acids that show strong fluorescent intensity changes upon sugar binding are reported: isoquinoline-7-boronic acid (7-IQBA) and phenoxathiin-4-boronic acid (4-POBA). INDEX WORDS: Chemosensor, Boronic acids, Saccharide recognition, Isoquinoline-7-boronic acid, Phenoxathiin-4-boronic acid, Fluorescence spectroscopy ARYLBORONIC ACIDS WITH STRONG FLUORESCENCE INTENSITY CHANGES UPON SUGAR BINDING
منابع مشابه
Screening of boronic acids for strong inhibition of the hydrolytic activity of a-chymotrypsin and for sugar sensing associated with a large fluorescence change
The inhibitory effect of arylboronic acids which act as a transition state analogue for certain peptidases is efficiently intensified by added saccharides: this finding enables us to control the enzyme activity by a combination of arylboronic acids and polyols including sugars. In particular, the combined system of 3-biphenylboronic acid and D-glucose strongly inhibited the hydrolysis reaction ...
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